| Challenger Tampere | 07/25 09:15 | 25 | Michon, Axel v Garcia-Lopez, Guillermo | 2-6,4-6 | |
| Challenger Scheveningen | 07/23 13:00 | 29 | [163] Garcia-Lopez, Guillermo v Bemelmans, Ruben [96] | 6-1,6-7,6-2 | |
| Challenger Scheveningen | 07/22 12:10 | 28 | [465] de Bakker, Thiemo v Garcia-Lopez, Guillermo [163] | Retired | |
| Challenger Scheveningen | 07/21 14:00 | 27 | [336] Botic Van De Zandschulp v Garcia-Lopez, Guillermo [163] | 4-6,3-6 | |
| Challenger Scheveningen | 07/20 14:00 | 26 | [179] Gonzalez, Maximo v Garcia-Lopez, Guillermo [163] | 7-5,3-6,4-6 | |
| Challenger Scheveningen | 07/18 13:35 | 25 | [298] Tallon Griekspoor v Garcia-Lopez, Guillermo [163] | 4-6,6-1,2-6 | |
| Challenger Bastad | 07/12 09:00 | 26 | Nedovyesov, Aleksandr v Garcia-Lopez, Guillermo | 6-2,6-4 | |
| Challenger Bastad | 07/10 09:20 | 25 | Fred Simonsson v Garcia-Lopez, Guillermo | 3-6,2-6 | |
| Challenger Marburg | 07/07 15:30 | 28 | [143] Garcia-Lopez, Guillermo v Filip Krajinovic [180] | 5-7,4-6 | |
| Challenger Marburg | 07/06 15:30 | 27 | [143] Garcia-Lopez, Guillermo v Sorgi, Joao Pedro [299] | 6-4,4-6,6-3 | |
| Challenger Marburg | 07/05 12:30 | 26 | [143] Garcia-Lopez, Guillermo v Bellotti, Riccardo [229] | 7-5,1-6,6-2 | |
| Challenger Marburg | 07/04 10:00 | 25 | [143] Garcia-Lopez, Guillermo v David Pichler [415] | 4-6,7-5,7-6 | |
| French Open, Paris, France | 06/02 10:25 | 25 | [6] Milos Raonic v Garcia-Lopez, Guillermo [153] | Retired | |
| French Open, Paris, France | 05/31 11:40 | 24 | Marco Trungelliti v Garcia-Lopez, Guillermo | 5-7,4-6,5-7 | |
| French Open, Paris, France | 05/28 09:00 | 23 | [153] Garcia-Lopez, Guillermo v Muller, Gilles [27] | 7-6,6-7,6-2,6-2 | |
| ATP - Madrid | 05/08 10:00 | 24 | [124] Garcia-Lopez, Guillermo v Marius Copil [104] | 6-7,6-4,6-7 | |
| ATP - Estoril | 05/02 15:10 | 25 | [52] Harrison, Ryan v Garcia-Lopez, Guillermo [120] | 6-3,2-6,6-2 | |
| ATP - Barcelone | 04/24 12:15 | 24 | Garcia-Lopez, Guillermo v Montanes, Albert | 4-6,4-6 | |
| ATP - Monte-Carlo | 04/17 11:00 | 24 | [56] Adrian Mannarino v Garcia-Lopez, Guillermo [100] | 1-6,6-3,6-4 | |
| ATP Monte Carlo Qual | 04/16 11:30 | 46 | [70] Damir Dzumhur v Garcia-Lopez, Guillermo [94] | 0-6,6-4,5-7 | |
| ATP Monte Carlo Qual | 04/15 12:30 | 45 | Diep, Florent v Garcia-Lopez, Guillermo | 3-6,2-6 | |
| ATP - Marrakech | 04/12 10:00 | 25 | [37] Lorenzi, Paolo v Garcia-Lopez, Guillermo [94] | 7-6,7-5 | |
| Sophia Antipolis, France | 04/07 14:00 | 27 | [91] Garcia-Lopez, Guillermo v Jozef Kovalik [127] | 6-7,7-5,1-6 | |
| Sophia Antipolis, France | 04/05 09:30 | 26 | [91] Garcia-Lopez, Guillermo v Lukas Rosol [162] | 6-0,5-7,6-3 | |
| Sophia Antipolis, France | 04/04 08:30 | 25 | [91] Garcia-Lopez, Guillermo v Corentin Moutet [395] | 6-2,7-5 | |
| ATP - Indian Wells | 03/11 02:15 | 23 | [89] Garcia-Lopez, Guillermo v Pella, Guido [145] | 6-4,5-7,2-6 | |
| ATP - Dubaï | 03/01 15:00 | 26 | [1] Andy Murray v Garcia-Lopez, Guillermo [97] | 6-2,6-0 | |
| ATP - Dubaï | 02/27 11:25 | 25 | [34] Troicki, Viktor v Garcia-Lopez, Guillermo [97] | 4-6,3-6 | |
| ATP - Delray Beach | 02/22 23:00 | 26 | Garcia-Lopez, Guillermo v Sock, Jack | 4-6,1-6 | |
| ATP - Delray Beach | 02/21 16:00 | 25 | Brown, Dustin v Garcia-Lopez, Guillermo | 3-6,3-6 |