| NCAAB | 12/02 21:00 | 1 | USC Upstate v Campbell | W | 80-73 | |
| NCAAB | 11/30 01:00 | 1 | Auburn v USC Upstate | L | 90-83 | |
| NCAAB | 11/27 21:00 | 1 | Coll Of Charleston v USC Upstate | L | 72-60 | |
| NCAAB | 11/23 00:00 | 1 | NC Charlotte 49ers v USC Upstate | W | 103-108 | |
| NCAAB | 11/19 22:30 | 1 | Charleston Southern v USC Upstate | W | 77-79 | |
| NCAAB | 11/18 00:00 | 1 |
USC Upstate
v
UNC Asheville
|
L | 57-73 | |
| NCAAB | 11/15 00:00 | 1 | USC Upstate v Mars Hill Lions | W | 91-66 | |
| NCAAB | 11/12 17:00 | 1 | Georgetown v USC Upstate | L | 105-60 | |
| NCAAB | 03/02 00:30 | 3 | North Florida v USC Upstate | L | 92-69 | |
| NCAAB | 02/26 00:00 | - | USC Upstate v NJIT | W | 72-71 | |
| NCAAB | 02/21 00:00 | - | North Florida v USC Upstate | L | 81-78 | |
| NCAAB | 02/19 00:00 | - | Jacksonville v USC Upstate | L | 81-76 | |
| NCAAB | 02/13 19:00 | - | USC Upstate v Stetson | W | 85-83 | |
| NCAAB | 02/12 00:00 | - |
USC Upstate
v
Florida Gulf Coast
|
L | 64-71 | |
| NCAAB | 02/06 19:00 | - |
USC Upstate
v
Lipscomb
|
L | 65-78 | |
| NCAAB | 02/02 00:00 | - | Kennesaw State v USC Upstate | L | 75-62 | |
| NCAAB | 01/30 22:00 | - |
Lipscomb
v
USC Upstate
|
W | 91-92 | |
| NCAAB | 01/28 00:00 | - | USC Upstate v Kennesaw State | L | 75-78 | |
| NCAAB | 01/23 19:00 | - | USC Upstate v Jacksonville | L | 68-77 | |
| NCAAB | 01/22 00:00 | - | USC Upstate v North Florida | L | 62-78 | |
| NCAAB | 01/17 00:00 | - |
Florida Gulf Coast
v
USC Upstate
|
L | 85-56 | |
| NCAAB | 01/15 00:00 | - | Stetson v USC Upstate | L | 89-86 | |
| NCAAB | 01/09 21:00 | - | NJIT v USC Upstate | W | 78-80 | |
| NCAAB | 01/06 00:00 | - | USC Upstate v North Carolina A&T | W | 78-68 | |
| NCAAB | 01/02 19:00 | - | USC Upstate v Kansas City | W | 70-68 | |
| NCAAB | 12/31 00:30 | - | USC Upstate v Lees-McRae Bobcats | W | 88-60 | |
| NCAAB | 12/22 02:00 | - | Colorado State v USC Upstate | L | 89-61 | |
| NCAAB | 12/17 01:00 | - | UAB v USC Upstate | L | 96-54 | |
| NCAAB | 12/15 00:00 | - | Navy v USC Upstate | W | 57-66 | |
| NCAAB | 12/12 00:00 | - | USC Upstate v North Greenville Crusaders | W | 70-58 |
L'équipe de basket-ball de USC Upstate, surnommée les Spartans, représente l'Université de Caroline du Sud Upstate dans le sport universitaire. L'équipe masculine participe à la division I de la NCAA et à la Big South Conference, tandis que l'équipe féminine participe à la division II et à la Peach Belt Conference. Les Spartans disputent leurs matchs à domicile dans l'USCU Arena, dans la ville de Spartanburg, en Caroline du Sud.
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