| NCAAB | 01/02 12:00 | - | Iowa State v USC Upstate | L | 72-48 | |
| NCAAB | 12/30 12:00 | - | Duquesne v USC Upstate | L | 84-66 | |
| NCAAB | 12/22 12:00 | - | Buffalo v USC Upstate | L | 80-66 | |
| NCAAB | 12/21 12:00 | - | UTEP v USC Upstate | L | 77-69 | |
| NCAAB | 12/18 12:00 | - | SMU v USC Upstate | W | 56-58 | |
| NCAAB | 12/15 12:00 | - | USC Upstate v Bluefield College Ramblin Rams | L | 77-93 | |
| NCAAB | 12/06 12:00 | - | USC Upstate v Brevard Tornados | W | 78-54 | |
| NCAAB | 12/01 12:00 | - | Wake Forest v USC Upstate | L | 72-48 | |
| NCAAB | 11/26 12:00 | - | Cincinnati v USC Upstate | L | 69-57 | |
| NCAAB | 11/24 12:00 | - | North Carolina Greensboro Spartans v USC Upstate | L | 93-76 | |
| NCAAB | 11/18 12:00 | - | Oregon State v USC Upstate | L | 65-46 | |
| NCAAB | 11/17 12:00 | - | IUPUI v USC Upstate | L | 80-54 | |
| NCAAB | 11/16 12:00 | - | Akron v USC Upstate | L | 64-60 | |
| NCAAB | 11/09 12:00 | - |
Utah
v
USC Upstate
|
L | 86-52 | |
| NCAAB | 12/06 12:00 | - | Appalachian State v USC Upstate | L | 84-74 |
L'équipe de basket-ball de USC Upstate, surnommée les Spartans, représente l'Université de Caroline du Sud Upstate dans le sport universitaire. L'équipe masculine participe à la division I de la NCAA et à la Big South Conference, tandis que l'équipe féminine participe à la division II et à la Peach Belt Conference. Les Spartans disputent leurs matchs à domicile dans l'USCU Arena, dans la ville de Spartanburg, en Caroline du Sud.
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