| WTA Moscow | 10/19 11:55 | 28 | [40] Anastasia Pavlyuchenkova v Muchova, Karolina [35] | 6-4,6-7,6-1 | |
| WTA Moscow | 10/18 16:05 | 27 | [42] Veronika Kudermetova v Anastasia Pavlyuchenkova [40] | 6-7,5-7 | |
| WTA Moscow | 10/17 17:10 | 26 | [121] Varvara Gracheva v Anastasia Pavlyuchenkova [40] | 7-5,4-6,2-6 | |
| WTA Moscow | 10/15 17:20 | 25 | [40] Anastasia Pavlyuchenkova v Maria Sakkari [29] | 5-7,6-1,6-3 | |
| WTA - Linz | 10/10 13:15 | 26 | [40] Anastasia Pavlyuchenkova v Kuzmova, Viktoria [53] | 6-2,2-6,4-6 | |
| WTA - Linz | 10/09 14:00 | 25 | [40] Anastasia Pavlyuchenkova v Haas, Barbara [147] | 6-3,6-3 | |
| WTA - Linz | 10/08 09:00 | 25 | Bertens, Kiki v Anastasia Pavlyuchenkova | Cancelled | |
| Pékin, Chine | 10/01 05:00 | 25 | [40] Anastasia Pavlyuchenkova v Sofia Kenin [16] | 3-6,2-6 | |
| Pékin, Chine | 09/30 04:30 | 24 | [36] Anastasia Pavlyuchenkova v Veronika Kudermetova [45] | 6-0,3-6,7-6 | |
| Wuhan, China | 09/23 10:40 | 24 | [36] Anastasia Pavlyuchenkova v Sofia Kenin [17] | 2-6,6-7 | |
| Osaka, Japon | 09/22 03:00 | 29 | [4] Naomi Osaka v Anastasia Pavlyuchenkova [41] | 6-2,6-3 | |
| Osaka, Japon | 09/21 08:05 | 28 | [15] Angelique Kerber v Anastasia Pavlyuchenkova [41] | 3-6,3-6 | |
| Osaka, Japon | 09/21 04:15 | 27 | [83] Doi, Misaki v Anastasia Pavlyuchenkova [41] | 2-6,2-6 | |
| Osaka, Japon | 09/19 08:30 | 26 | [41] Anastasia Pavlyuchenkova v Bertens, Kiki [8] | 6-1,7-5 | |
| Osaka, Japon | 09/16 08:00 | 25 | [28] Dayana Yastremska v Anastasia Pavlyuchenkova [41] | 3-6,1-6 | |
| US Open Women | 08/29 20:30 | 24 | [45] Anastasia Pavlyuchenkova v Bertens, Kiki [7] | 5-7,4-6 | |
| US Open Women | 08/27 18:40 | 23 | [81] Parmentier, Pauline v Anastasia Pavlyuchenkova [45] | 1-6,6-7 | |
| WTA Cincinnati | 08/10 18:35 | 45 | [44] Anastasia Pavlyuchenkova v Zarina Diyas [79] | 1-6,6-7 | |
| WTA Toronto | 08/07 19:30 | 25 | [82] Jelena Ostapenko v Anastasia Pavlyuchenkova [44] | 6-2,2-6,6-4 | |
| WTA Toronto | 08/07 00:15 | 24 | [44] Anastasia Pavlyuchenkova v Aryna Sabalenka [9] | 3-6,6-3,7-5 | |
| WTA Washington | 07/29 17:00 | 25 | [105] Mchale, Christina v Anastasia Pavlyuchenkova [43] | 6-2,4-6,7-5 | |
| Wimbledon Women | 07/02 12:30 | 23 | [46] Anastasia Pavlyuchenkova v Bencic, Belinda [13] | 2-6,3-6 | |
| French Open Women | 05/27 11:00 | 23 | [44] Anastasia Pavlyuchenkova v Minella, Mandy [100] | 4-6,2-6 | |
| WTA - Rome | 05/14 09:00 | 24 | [39] Maria Sakkari v Anastasia Pavlyuchenkova [36] | 6-1,7-5 | |
| WTA - Rome | 05/13 09:00 | 24 | Donna Vekic v Anastasia Pavlyuchenkova | Cancelled | |
| WTA - Madrid | 05/04 10:30 | 24 | [35] Anastasia Pavlyuchenkova v Jelena Ostapenko [31] | 2-6,1-6 | |
| WTA - Stuttgart | 04/25 13:05 | 26 | [34] Anastasia Pavlyuchenkova v Kontaveit, Anett [15] | 3-6,2-6 | |
| WTA - Stuttgart | 04/24 16:30 | 25 | [34] Anastasia Pavlyuchenkova v Goerges, Julia [17] | Retired | |
| Fed Cup, Groupe Mondial | 04/21 11:00 | - | [34] Anastasia Pavlyuchenkova v Martina Trevisan [146] | 6-4,6-3 | |
| Fed Cup, Groupe Mondial | 04/20 13:25 | - | [34] Anastasia Pavlyuchenkova v Jasmine Paolini [178] | 7-6,7-6 |