| ATP Paris Qual | 10/29 12:15 | 46 | [105] Vasek Pospisil v Mathieu, Paul-Henri [265] | 6-3,6-4 | |
| ATP Paris Qual | 10/28 15:30 | 45 | [265] Mathieu, Paul-Henri v Daniil Medvedev [67] | 6-4,6-4 | |
| ATP Basel Qual | 10/21 15:00 | 45 | [68] Gojowczyk, Peter v Mathieu, Paul-Henri [269] | 6-7,7-5,6-4 | |
| Orleans, France | 09/29 15:00 | 27 | [252] Mathieu, Paul-Henri v Benneteau, Julien [110] | 4-6,1-6 | |
| Orleans, France | 09/28 14:10 | 26 | [81] Mikhail Kukushkin v Mathieu, Paul-Henri [252] | 6-7,1-6 | |
| Orleans, France | 09/27 16:00 | 25 | [252] Mathieu, Paul-Henri v Gleb Sakharov [184] | 6-3,6-1 | |
| Metz, France | 09/20 16:00 | 25 | [252] Mathieu, Paul-Henri v Laaksonen, Henri [113] | 5-7,2-6 | |
| US Open, New York, USA, Qualifying | 08/23 17:05 | 44 | [156] Ramkumar Ramanathan v Mathieu, Paul-Henri [213] | 6-4,6-4 | |
| Kitzbühel, Autriche, Qualifications | 07/29 13:40 | 45 | [210] Mathieu, Paul-Henri v Thiago Monteiro [114] | 2-6,1-6 | |
| ATP Bastad | 07/18 10:30 | 25 | [119] Renzo Olivo v Mathieu, Paul-Henri [166] | 6-2,6-4 | |
| ATP Bastad Qual | 07/17 14:15 | 46 | [166] Mathieu, Paul-Henri v Mayer, Leonardo [134] | 6-2,3-6,2-6 | |
| ATP Bastad Qual | 07/17 09:00 | 45 | [166] Mathieu, Paul-Henri v Arvidsson, Isak [258] | 6-2,6-2 | |
| Braunchsweig, Germany | 07/11 09:00 | 25 | [93] Norbert Gombos v Mathieu, Paul-Henri [138] | 6-1,6-1 | |
| Wimbledon Qual | 06/29 15:00 | - | [92] Andrey Rublev v Mathieu, Paul-Henri [138] | 6-4,1-6,7-6,6-4 | |
| Wimbledon Qual | 06/28 17:20 | 45 | [169] Gonzalez, Maximo v Mathieu, Paul-Henri [138] | 1-6,4-6 | |
| Wimbledon Qual | 06/26 14:05 | 44 | [241] Reuter, Yannik v Mathieu, Paul-Henri [138] | 6-7,2-6 | |
| Ilkley, Great Britain | 06/20 16:25 | 25 | [131] Mathieu, Paul-Henri v Illya Marchenko [117] | Retired | |
| Lyon, France | 06/16 16:50 | 27 | [125] Mathieu, Paul-Henri v Nedovyesov, Aleksandr [244] | 2-6,2-6 | |
| Lyon, France | 06/15 17:50 | 26 | Mathieu, Paul-Henri v Marco Trungelliti | 6-3,5-7,6-3 | |
| Lyon, France | 06/13 14:30 | 25 | [125] Mathieu, Paul-Henri v Jahn, Jeremy [229] | 6-3,6-1 | |
| French Open, Paris, France | 05/29 11:45 | 23 | [120] Mathieu, Paul-Henri v David Goffin [12] | 2-6,2-6,2-6 | |
| French Open Qual | 05/26 11:10 | 46 | [119] Mathieu, Paul-Henri v Denis Kudla [171] | 6-3,6-4 | |
| French Open Qual | 05/24 13:30 | 45 | [119] Mathieu, Paul-Henri v Gonzalez, Alejandro [417] | 7-5,6-1 | |
| French Open Qual | 05/22 14:10 | 44 | [119] Mathieu, Paul-Henri v Tatsuma Ito [173] | 6-7,6-2,6-2 | |
| ATP - Estoril | 05/02 17:20 | 25 | [116] Mathieu, Paul-Henri v Sousa, Pedro [172] | Retired | |
| ATP Monte Carlo Qual | 04/15 14:00 | 45 | [59] Jan-Lennard Struff v Mathieu, Paul-Henri [115] | 4-6,6-2,7-6 | |
| ATP - Marrakech | 04/11 15:50 | 25 | [115] Mathieu, Paul-Henri v Quinzi, Gianluigi [304] | 6-7,3-6 | |
| Sophia Antipolis, France | 04/05 14:10 | 26 | [152] Marton Fucsovics v Mathieu, Paul-Henri [108] | 6-4,1-6,6-3 | |
| Sophia Antipolis, France | 04/04 10:10 | 25 | [196] Laslo Djere v Mathieu, Paul-Henri [108] | 4-6,3-6 | |
| Challenger Wroclaw | 03/04 13:00 | 28 | Mathieu, Paul-Henri v Melzer, Jurgen | 6-7,1-6 |