[12] San Lorenzo 0-0 River Plate [7] 2020-08-25 23:00
Stadium: Estadio Gunther Vogel Round: 16
Referee: Juan Eduardo Lopez Home Manager: Cristian Martinez Away Manager: Celso Ayala
Face à face
| Paraguay - Division Profesional | 2020/02/17 21:30 | River Plate v San Lorenzo | L | 4-2 |
| Paraguay - Division Profesional | 2019/12/15 21:00 | San Lorenzo v River Plate | W | 2-0 |
| Paraguay - Division Profesional | 2019/09/24 22:00 | River Plate v San Lorenzo | D | 0-0 |
| Paraguay - Division Profesional | 2019/03/23 23:15 | River Plate v San Lorenzo | L | 2-1 |
| Paraguay - Division Profesional | 2019/01/22 21:00 | San Lorenzo v River Plate | W | 1-0 |
| Paraguay - Division Profesional | 2018/06/24 14:30 | River Plate v San Lorenzo | L | 1-0 |
| Division intermédiaire | 2018/03/18 12:30 | San Lorenzo v River Plate | D | 2-2 |
| Division intermédiaire | 2014/10/12 13:00 | San Lorenzo v River Plate | W | 2-0 |
| Division intermédiaire | 2014/06/21 19:00 | River Plate v San Lorenzo | D | 1-1 |
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