[38] Karen Khachanov 7-6,7-6 Isner, John [9] 2018-08-09 22:40
Stadium: National Bank Grandstand Round: 26 Ground: Hardcourt outdoor
Face à face
| Open de France | 2017/06/03 14:15 | Isner, John v Karen Khachanov | 6-7,3-6,7-6,6-7 |
Home History
| Toronto, Canada | 2018/08/08 16:00 | Carreno-Busta, Pablo v Karen Khachanov | 4-6,6-7 |
| Toronto, Canada | 2018/08/07 15:00 | Filip Krajinovic v Karen Khachanov | 3-6,2-6 |
| Washington, USA | 2018/08/01 16:00 | Denis Kudla v Karen Khachanov | 6-2,6-3 |
| Wimbledon, London, Great Britain | 2018/07/09 17:50 | Karen Khachanov v Novak Djokovic | 4-6,2-6,2-6 |
| Wimbledon, London, Great Britain | 2018/07/07 14:40 | Karen Khachanov v Frances Tiafoe | 4-6,4-6,7-6,6-2,6-1 |
| Wimbledon, London, Great Britain | 2018/07/05 13:25 | Baghdatis, Marcos v Karen Khachanov | 3-6,4-6,6-3,7-6,5-7 |
| Wimbledon, London, Great Britain | 2018/07/03 14:05 | FERRER D. v Karen Khachanov | 1-6,6-7,6-3,5-7 |
| ATP Halle | 2018/06/22 13:30 | Karen Khachanov v Bautista-Agut, Roberto | 3-6,7-6,3-6 |
Away History
| Toronto, Canada | 2018/08/08 20:00 | Pierre-Hugues Herbert v Isner, John | 6-7,2-6 |
| Washington, USA | 2018/08/02 21:30 | Noah Rubin v Isner, John | 6-4,7-6 |
| Atlanta, USA | 2018/07/29 21:00 | Isner, John v Harrison, Ryan | 5-7,6-3,6-4 |
| Atlanta, USA | 2018/07/28 19:00 | Isner, John v Ebden, Matthew | 6-4,6-7,6-1 |
| Atlanta, USA | 2018/07/27 18:00 | Isner, John v Zverev, Mischa | 7-5,4-6,6-1 |
| Atlanta, USA | 2018/07/25 23:00 | Isner, John v Alex De Minaur | 6-3,6-2 |
| Wimbledon, London, Great Britain | 2018/07/13 12:00 | Anderson, Kevin v Isner, John | 7-6,6-7,6-7,6-4,26-24 |
| Wimbledon, London, Great Britain | 2018/07/11 16:35 | Milos Raonic v Isner, John | 7-6,6-7,4-6,3-6 |
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