| Reserve League | 2021/10/31 17:00 | Uni. de Catolica v Independiente Del Valle Reserve | D | 1-1 |
| Reserve League | 2021/10/17 15:00 | Csd Macara v Uni. de Catolica | D | 1-1 |
| Reserve League | 2021/10/08 17:00 | Uni. de Catolica v LDU Quito (R) | W | 3-2 |
| Reserve League | 2021/10/01 20:00 | CS Emelec v Uni. de Catolica | L | 4-2 |
| Reserve League | 2021/09/17 17:00 | Uni. de Catolica v Orense Reserves | D | 1-1 |
| Reserve League | 2021/08/06 15:00 | Mushuc Runa SC Reserve v Uni. de Catolica | W | 0-2 |
| Reserve League | 2021/07/23 16:32 | Tecnico Uni. v Uni. de Catolica | W | 0-2 |
| Reserve League | 2021/07/09 19:00 | Csd Macara v Uni. de Catolica | W | 0-1 |
| Reserve League | 2021/08/06 15:00 | Barcelona SC v Club 9 de Octubre Reserves | D | 1-1 |
| Reserve League | 2021/07/03 20:00 | Club 9 de Octubre Reserves v Orense Reserves | W | 3-1 |
| Reserve League | 2021/06/26 19:00 | Manta FC Reserves v Club 9 de Octubre Reserves | L | 1-0 |