| Seconde Division | 2021/12/04 17:00 | Real Betis Futsal B v Ciudad de Mostoles | W | 8-4 |
| Seconde Division | 2021/11/27 17:00 | U. A. Ceuti v Real Betis Futsal B | L | 4-2 |
| Seconde Division | 2021/11/20 15:00 | Real Betis Futsal B v Nitida Alzira FS | L | 1-2 |
| Seconde Division | 2021/11/13 16:00 | Etb Calvia v Real Betis Futsal B | W | 3-6 |
| Seconde Division | 2021/11/07 15:00 | Real Betis Futsal B v FC Barcelona B | L | 3-4 |
| Seconde Division | 2021/10/30 15:30 | Bisontes Castellon v Real Betis Futsal B | L | 5-3 |
| Seconde Division | 2021/10/23 16:00 | Talavera v Real Betis Futsal B | L | 7-1 |
| Seconde Division | 2021/10/17 10:30 | Real Betis Futsal B v At. Benavente | L | 1-3 |
| Seconde Division | 2021/12/08 16:00 | Inter FS B v Talavera | W | 5-3 |
| Seconde Division | 2021/12/04 18:00 | At. Benavente v Inter FS B | D | 2-2 |
| Seconde Division | 2021/11/28 11:45 | Inter FS B v Leganes | W | 3-2 |
| Seconde Division | 2021/11/20 17:00 | Parrulo Ferrol v Inter FS B | D | 2-2 |
| Seconde Division | 2021/11/14 11:45 | Inter FS B v Peniscola | L | 4-5 |
| Seconde Division | 2021/11/06 17:00 | El Ejido v Inter FS B | L | 4-0 |
| Seconde Division | 2021/10/30 14:00 | Inter FS B v Antequera | L | 1-5 |
| Seconde Division | 2021/10/23 16:30 | Colo Colo Zaragoza v Inter FS B | D | 2-2 |