[1] Club América 2-1 Santos Laguna [11] 2021-10-20 00:05
Stadium: Stade Azteca Round: 14
Referee: Marco Antonio Ortiz Nava Home Manager: Santiago Solari Away Manager: Guillermo Almada
Face à face
| Matchs amicaux | 2021/07/05 00:30 | Club América v Santos Laguna | W | 1-0 |
| Mexique - Liga MX | 2021/02/01 01:06 | Santos Laguna v Club América | D | 1-1 |
| Mexique - Liga MX | 2020/08/14 02:00 | Club América v Santos Laguna | W | 3-1 |
| Mexique - Liga MX | 2019/11/03 01:00 | Club América v Santos Laguna | L | 1-2 |
| Mexique - Liga MX | 2019/04/28 00:00 | Club América v Santos Laguna | W | 1-0 |
| Clubs internationaux - matchs amicaux | 2018/12/29 22:30 | Club América v Santos Laguna | D | 1-1 |
| Mexique - Liga MX | 2018/11/12 00:00 | Santos Laguna v Club América | D | 1-1 |
| Mexique - Liga MX | 2018/05/14 00:00 | Club América v Santos Laguna | D | 2-2 |
Home History
| Mexique - Liga MX | 2021/10/17 00:00 | Atletico San Luis v Club América | W | 0-1 |
| Clubs internationaux - matchs amicaux | 2021/10/09 01:30 | Club América v Unam Pumas | L | 0-1 |
| Mexique - Liga MX | 2021/10/03 22:00 | Club América v Unam Pumas | W | 2-0 |
| Mexique - Liga MX | 2021/09/29 02:05 | Pachuca v Club América | D | 1-1 |
| Mexique - Liga MX | 2021/09/26 02:00 | Club América v Chivas Guadalajara | D | 0-0 |
| Mexique - Liga MX | 2021/09/19 00:00 | Toluca v Club América | L | 3-1 |
| Coupe des champions CONCACAF | 2021/09/16 01:00 | Philadelphia Union v Club América | W | 0-2 |
| Mexique - Liga MX | 2021/09/12 02:00 | Club América v Mazatlan FC | W | 2-0 |
Away History
| Mexique - Liga MX | 2021/10/17 00:00 | Pachuca v Santos Laguna | D | 1-1 |
| Mexique - Liga MX | 2021/10/03 00:06 | Santos Laguna v Mazatlan FC | W | 1-0 |
| Mexique - Liga MX | 2021/09/27 00:06 | Santos Laguna v Monterrey | L | 1-2 |
| Mexique - Liga MX | 2021/09/20 02:06 | Santos Laguna v Puebla | D | 1-1 |
| Leagues Cup | 2021/09/15 02:00 | Seattle Sounders v Santos Laguna | L | 1-0 |
| Mexique - Liga MX | 2021/09/11 02:06 | Tijuana v Santos Laguna | L | 2-1 |
| Mexique - Liga MX | 2021/08/29 23:00 | Santos Laguna v Juárez FC | W | 2-0 |
| Mexique - Liga MX | 2021/08/22 00:00 | Leon v Santos Laguna | D | 1-1 |
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