[9] Isner, John 1-6,4-6 Federer, Roger [5] 2019-03-31 17:00
Stadium: Stadium Round: 29 Ground: Hardcourt outdoor
Face à face
| Laver Cup, Matchs en Simple | 2018/09/23 19:00 | Federer, Roger v Isner, John | 6-7,7-6,10-7 |
| Laver Cup, Matchs en Simple | 2018/09/23 18:30 | Federer, Roger v Isner, John | 6-7,7-6,1-0 |
| US Open, New York, USA | 2015/09/08 01:00 | Isner, John v Federer, Roger | 6-7,6-7,5-7 |
Home History
| ATP - Miami | 2019/03/29 17:00 | Isner, John v Felix Auger Aliassime | 7-6,7-6 |
| ATP - Miami | 2019/03/27 20:20 | Bautista-Agut, Roberto v Isner, John | 6-7,6-7 |
| ATP - Miami | 2019/03/26 16:00 | Kyle Edmund v Isner, John | 6-7,6-7 |
| ATP - Miami | 2019/03/24 16:00 | Albert Ramos-Vinolas v Isner, John | 5-7,6-7 |
| ATP - Miami | 2019/03/22 18:25 | Lorenzo Sonego v Isner, John | 6-7,6-7 |
| ATP - Indian Wells | 2019/03/13 21:10 | Isner, John v Karen Khachanov | 4-6,6-7 |
| ATP - Indian Wells | 2019/03/12 21:20 | Isner, John v Pella, Guido | 6-3,6-4 |
| ATP - Indian Wells | 2019/03/10 23:15 | Isner, John v Alexei Popyrin | 6-0,6-2 |
Away History
| ATP - Miami | 2019/03/29 23:00 | Federer, Roger v Denis Shapovalov | 6-2,6-4 |
| ATP - Miami | 2019/03/28 23:40 | Anderson, Kevin v Federer, Roger | 0-6,4-6 |
| ATP - Miami | 2019/03/27 19:00 | Daniil Medvedev v Federer, Roger | 4-6,2-6 |
| ATP - Miami | 2019/03/25 19:35 | Filip Krajinovic v Federer, Roger | 5-7,3-6 |
| ATP - Miami | 2019/03/23 21:35 | Radu Albot v Federer, Roger | 6-4,5-7,3-6 |
| ATP - Indian Wells | 2019/03/17 22:35 | Dominic Thiem v Federer, Roger | 3-6,6-3,7-5 |
| ATP - Indian Wells | 2019/03/15 18:00 | Hubert Hurkacz v Federer, Roger | 4-6,4-6 |
| ATP - Indian Wells | 2019/03/13 21:10 | Kyle Edmund v Federer, Roger | 1-6,4-6 |
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